- Safety Equipment & Supplies, Jefferson
- Sand Gravel & Aggregate, Jefferson
- Sandwich Shop Restaurants, Jefferson
- School - Catholic, Jefferson
- School - Christian, Jefferson
- Screen Printing, Jefferson
- Seafood Restaurants, Jefferson
- Secondary Schools, Jefferson
- Security Brokers & Dealers, Jefferson
- Senior Citizens Service & Health Organizations, Jefferson
- Septic Tank Installation & Repair, Jefferson - Septic Systems
- Septic Tank Pumping & Cleaning, Jefferson - Septic Systems
- Septic Tanks & Septic Systems Contractors, Jefferson - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewer & Drain Cleaning & Repair, Jefferson - Drain Cleaner & Installation Services
- Sheriff's Department, Jefferson
- Shoe Stores, Jefferson - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Jefferson
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- Snacks & Desserts, Jefferson
- Snow Removal Services, Jefferson - Snow Plow Service
- Snowmobile Dealers, Jefferson - Parts, Gear, Clothing & Accessories
- Social Clubs & Organizations, Jefferson
- Social Service Organizations Volunteer Services, Jefferson
- Social Services & Welfare, Jefferson
- Special Interest Schools Or Instruction, Jefferson
- Specialty Animal Services, Jefferson
- Specialty Goods Storage, Jefferson
- Specialty Stores, Jefferson
- Sports Medicine, Jefferson - Doctors, Physicians & Surgeons
- Staffing & Support Services, Jefferson
- State Government, Jefferson
- Steel Bar Sheet Strip Tube Etcetera Manufacturers, Jefferson
- Steel Manufacturers, Jefferson
- Stocks & Bond Brokers, Jefferson
- Swimming Pools, Jefferson
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