- Safe & Vault, Platteville
- Sand Gravel & Aggregate, Platteville
- Sandblasting, Platteville - General Contractors
- Sandwich Shop Restaurants, Platteville
- Satellite Descrambling & Programming Service, Platteville
- Satellite Dish Antennas & Equipment Dealers, Platteville
- Satellite TV Service, Platteville
- Scrap & Waste Materials, Platteville
- Screen Printing, Platteville
- Seafood Restaurants, Platteville
- Secondary Schools, Platteville
- Security & Commodity Brokers, Platteville
- Security Alarm Systems - Home & Business, Platteville
- Security Brokers & Dealers, Platteville
- Security Control Systems & Monitoring, Platteville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Platteville
- Senior Citizens Housing, Platteville
- Septic Tank Installation & Repair, Platteville - Septic Systems
- Septic Tank Pumping & Cleaning, Platteville - Septic Systems
- Septic Tanks & Septic Systems Contractors, Platteville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewer & Drain Cleaning & Repair, Platteville - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Platteville
- Shopping & Shopping Services, Platteville
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- Siding Contractors, Platteville - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Signs, Platteville
- Snacks & Desserts, Platteville
- Snow Removal Services, Platteville - Snow Plow Service
- Social Services & Welfare, Platteville
- Societies & Foundation Associations, Platteville
- Sororities, Platteville
- Special Events & Party Supply Rental, Platteville
- Speciality Food Stores, Platteville
- Specialty Animal Services, Platteville
- Specialty Goods Storage, Platteville
- Specialty Stores, Platteville
- Speech & Hearing Specialists, Platteville
- Sporting Goods Stores, Platteville
- Staffing & Support Services, Platteville
- State Government, Platteville
- Stitching Services, Platteville
- Stock & Bond Brokers & Dealers, Platteville
- Stocks & Bond Brokers, Platteville
- Stone, Platteville
- Stone & Rock Quarry, Platteville - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Structural Engineer, Platteville
- Swimming Pools Supplies, Equipment & Accessories, Platteville
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